Run first introduces us to Diane Sherman (Paulson) shortly after she has given birth, with doctors working diligently to try and save the life of her incredibly small baby. Seventeen years later we are then introduced to Chloe (Allen), who lives with a number of conditions – including an irregular heartbeat, diabetes, asthma, and paraplegia – but is ready to start her independent life in college away from her mom. Publically Diane makes it seem like she is excited to see her daughter head off to a university after a life of home-schooling, but when they are alone she is overly controlling, and treats Chloe like a child.

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